I can't fix everything

There are some things I can't fix. I don't have the know-how or the tools or both. Sometimes a problem doesn't want to get fixed. Imagine a sentient wheel that keeps on squeaking so that it can keep getting oil even if it doesn't need oil and everyone around the wheel is out of oil. Okay so it's not a wheel that is my problem but the situation is similar. What is one to do when the going not only gets tough but the people around you are quitting and even the road wants to stop.